Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Aldose reductase (AR) (315/316 > 99%)† (Homo sapiens (Human)) | BDBM50151407![]() ((2S,4R)-2-AMINOFORMYL-6-FLUORO-SPIRO[CHROMAN-4,4'-...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Monash University (Parkville Campus) Curated by ChEMBL | Assay Description Binding affinity for human Aldose reductase 2 expressed in Escherichia coli | J Med Chem 47: 4530-7 (2004) Article DOI: 10.1021/jm0497794 BindingDB Entry DOI: 10.7270/Q2M9085V | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |