Found 6 Enz. Inhib. hit(s) for PDB: 3DCU 
Affinity DataEC50: 87nMpH: 7.5 T: 2°CAssay Description:The assay measures ligand-mediated interaction of the SRC-1 peptide with the FXR ligand binding domain, using biotinylated FXR LBD coupled to allophy...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataEC50: 68nMAssay Description:The cell-based assay measures the ligand-mediated luminescense resulting from FXR-induced transcription of a luciferase reporter. FXR and the lucifer...More data for this Ligand-Target Pair
Affinity DataEC50: 68nMAssay Description:Agonist activity at human FXR LBD transfected in african green monkey CV1 cells after overnight incubation by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 68nMAssay Description:Agonist activity at human FXR LBD iexpressed in monkey CV-1 cells assessed as transactivation of luciferase reporter gene expressionMore data for this Ligand-Target Pair
Affinity DataEC50: 87nMAssay Description:Agonist activity at human amino-terminal polyhistidine-tagged FXR alpha LBD (amino acids 237 to 472) assessed as cofactor peptide SRC-1 interaction w...More data for this Ligand-Target Pair
Affinity DataEC50: 87nMAssay Description:Agonist activity at human FXR LBD assessed as SRC1 peptide recruitment by FRET assayMore data for this Ligand-Target Pair
