Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ML-IAP-BIR (122/132 = 92%)† (Homo sapiens (Human)) | BDBM27942![]() ((2S)-1-[(2S)-2-[(2S)-2-aminopropanamido]-3-methylb...) | PDB MMDB B.MOAD GoogleScholar | KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | 43 | -41.6 | n/a | n/a | n/a | n/a | n/a | 7.2 | 22 |
Genentech Inc | Assay Description Samples for fluorescence polarization affinity measurements were prepared by addition of serial dilutions of target protein to each well containing a... | J Med Chem 52: 1723-30 (2009) Article DOI: 10.1021/jm801450c BindingDB Entry DOI: 10.7270/Q2WH2N9H | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |