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Found 3 Enz. Inhib. hit(s) for PDB: 3IND
TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303718(5-Adamantan-1-yl-2-amino-3-methyl-5-phenyl-3,5-dih...)
Affinity DataIC50:  1.53E+3nMAssay Description:Inhibition of human BACE1 by FRET based peptide cleavage assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303718(5-Adamantan-1-yl-2-amino-3-methyl-5-phenyl-3,5-dih...)
Affinity DataIC50:  1.53E+3nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303718(5-Adamantan-1-yl-2-amino-3-methyl-5-phenyl-3,5-dih...)
Affinity DataEC50:  930nMAssay Description:Inhibition of BACE1 expressed in CHOK1 cells coexpressing human recombinant wild type APP assessed as blockade of amyloid beta production by ELISAMore data for this Ligand-Target Pair