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Report error Found 2 Enz. Inhib. hit(s) for PDB: 3IO7
TargetTyrosine-protein kinase JAK2(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50378535(CHEMBL1204012)
Affinity DataKi:  7nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetTyrosine-protein kinase JAK2(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50378535(CHEMBL1204012)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of JAK2-mediated STAT5 phosphorylation in GMCSF-stimulated human TF1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)