Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) for PDB: 3KMX
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM114543((4-butoxy-3-chloranyl-phenyl)methyl carbamimidothi...)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibition of BACE1 mediated human Swedish amyloid precursor protein peptide hydrolysis by HTRF assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM114543((4-butoxy-3-chloranyl-phenyl)methyl carbamimidothi...)
Affinity DataIC50:  2.10E+5nMAssay Description:Inhibition of BACE1 by HTRF assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM114543((4-butoxy-3-chloranyl-phenyl)methyl carbamimidothi...)
Affinity DataKd:  1.50E+4nMAssay Description:Binding affinity to BACE1 by fragment-based NMR screening assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM114543((4-butoxy-3-chloranyl-phenyl)methyl carbamimidothi...)
Affinity DataKd:  1.50E+4nMAssay Description:Inhibition of BACE1 by fragment-based NMR screening methodMore data for this Ligand-Target Pair