PDB code 3KV2
Identical Ligands in BindingDB
Found 2 hits Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Arginase-1
(281/323 = 87%)† (Rattus norvegicus) | BDBM50008099
 (CHEMBL1234777)Show InChI InChI=1S/C5H12N4O3/c6-3(4(10)11)1-2-8-5(7)9-12/h3,12H,1-2,6H2,(H,10,11)(H3,7,8,9)/t3-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar
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CHEMBL DrugBank PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of rat liver arginase |
Eur J Med Chem 76: 132-44 (2014)
Article DOI: 10.1016/j.ejmech.2014.02.008 BindingDB Entry DOI: 10.7270/Q2T43VM0 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Arginase-1
(322/322 = 100%)† (Homo sapiens (Human)) | BDBM50008099
 (CHEMBL1234777)Show InChI InChI=1S/C5H12N4O3/c6-3(4(10)11)1-2-8-5(7)9-12/h3,12H,1-2,6H2,(H,10,11)(H3,7,8,9)/t3-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar
| Purchase
CHEMBL DrugBank PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article
| n/a | n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity to arginase 1 (unknown origin) |
Citation and Details
Article DOI: null BindingDB Entry DOI: 10.7270/Q2736THR |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
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Search BindingMOAD for More Affinity Data:
* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output