Affinity Data by PDB ID

PDB code 3KV2

Found 2 hits Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Arginase-1 (281/323 = 87%)^† (Rattus norvegicus)	BDBM50008099 (CHEMBL1234777) Show SMILES N[C@@H](CCNC(=N)NO)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of rat liver arginase				Eur J Med Chem 76: 132-44 (2014) Article DOI: 10.1016/j.ejmech.2014.02.008 BindingDB Entry DOI: 10.7270/Q2T43VM0
The University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Arginase-1 (322/322 = 100%)^† (Homo sapiens (Human))	BDBM50008099 (CHEMBL1234777) Show SMILES N[C@@H](CCNC(=N)NO)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PDB Article	n/a	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to arginase 1 (unknown origin)				Citation and Details Article DOI: null BindingDB Entry DOI: 10.7270/Q2736THR
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)

_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output