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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALK3 (286/334 = 86%)† (Mus musculus) | BDBM50262079 (4-(6-(4-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet  | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 14.3 | n/a | n/a | n/a | n/a | n/a | n/a |
Massachusetts Institute of Technology | ACS Chem Biol 8: 1291-302 (2013) | ||||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
| Bone morphogenetic protein receptor type-1B (BMPR1B) (Homo sapiens (Human)) | BDBM50262079 (4-(6-(4-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyri...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center Curated by ChEMBL | Assay Description Inhibition of ALK6 (unknown origin) | Bioorg Med Chem Lett 23: 3248-52 (2013) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
