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PDB code 3Q3K

Compile Data Set for Download or QSAR

Identical Ligands in BindingDB

Found 1 hit Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X

  (54/54 = 100%)
(Homo sapiens (Human))
BDBM50340857
PNG
(CHEMBL1761615 | N-(2-(5-chloro-1H-indole-2-carboxa...)
Show SMILES CN1CCc2nc(sc2C1)C(=O)Nc1ccccc1NC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C23H20ClN5O2S/c1-29-9-8-18-20(12-29)32-23(28-18)22(31)27-17-5-3-2-4-16(17)26-21(30)19-11-13-10-14(24)6-7-15(13)25-19/h2-7,10-11,25H,8-9,12H2,1H3,(H,26,30)(H,27,31)
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n/an/a 7.40n/an/an/an/an/an/a



Daiichi Sankyo Co, Ltd

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a using S2222 chromogenic substrate by spectrophotometric analysis


Bioorg Med Chem Lett 21: 2133-40 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.132
BindingDB Entry DOI: 10.7270/Q2MK6D60
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)

Search BindingMOAD for More Affinity Data:

* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
Identities from BLAST output