Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) for PDB: 3QD0
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50341239((3S,6R)-1-[2-Amino-6-(3-amino-1H-indazol-6-yl)-4-p...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50341239((3S,6R)-1-[2-Amino-6-(3-amino-1H-indazol-6-yl)-4-p...)
Affinity DataIC50:  327nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50341239((3S,6R)-1-[2-Amino-6-(3-amino-1H-indazol-6-yl)-4-p...)
Affinity DataIC50:  333nMAssay Description:Inhibition of PDK1-mediated RSK phosphorylation at Ser221 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50341239((3S,6R)-1-[2-Amino-6-(3-amino-1H-indazol-6-yl)-4-p...)
Affinity DataIC50: >2.93E+4nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Ser473 in human PC3 cells by ELISAMore data for this Ligand-Target Pair