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Found 7 Enz. Inhib. hit(s) for PDB: 3RT8
TargetGlutamate receptor 2(Rattus norvegicus)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50060632((S)-2-Amino-3-(5-chloro-2,4-dioxo-3,4-dihydro-2H-p...)
Affinity DataKi:  45nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR2(R) expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50060632((S)-2-Amino-3-(5-chloro-2,4-dioxo-3,4-dihydro-2H-p...)
Affinity DataKi:  53nMAssay Description:Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 1(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50060632((S)-2-Amino-3-(5-chloro-2,4-dioxo-3,4-dihydro-2H-p...)
Affinity DataKi:  65nMAssay Description:Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 4(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50060632((S)-2-Amino-3-(5-chloro-2,4-dioxo-3,4-dihydro-2H-p...)
Affinity DataKi:  451nMAssay Description:Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 3(RAT)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50060632((S)-2-Amino-3-(5-chloro-2,4-dioxo-3,4-dihydro-2H-p...)
Affinity DataKi:  451nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR3 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 4(Rattus norvegicus)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50060632((S)-2-Amino-3-(5-chloro-2,4-dioxo-3,4-dihydro-2H-p...)
Affinity DataKi:  561nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR4 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 2(Rattus norvegicus)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50060632((S)-2-Amino-3-(5-chloro-2,4-dioxo-3,4-dihydro-2H-p...)
Affinity DataEC50:  2.11E+3nMAssay Description:Agonist activity at cyclothiazide-desensitized rat recombinant flip iGluR2(Q) expressed in Xenopus laevis oocytes by two electrode voltage-clamp elec...More data for this Ligand-Target Pair