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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Aromatase (CYP19) (503/503 = 100%)† (Homo sapiens (human)) | BDBM50025428 (10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dode...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet  | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku College of Pharmacy Curated by ChEMBL | Assay Description Binding affinity for aromatase cytochrome P45019A1 by analysis of Dixon plot | Citation and Details | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
| Aromatase (CYP19) (503/503 = 100%)† (Homo sapiens (human)) | BDBM50025428 (10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dode...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku College of Pharmacy Curated by ChEMBL | Assay Description In vitro competetitive inhibitory activity was measured on Cytochrome P450 19A1 of human placental microsomes | Citation and Details | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
