Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 19A1 (503/503 = 100%)† (Homo sapiens (Human)) | BDBM50025428![]() (10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dode...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku College of Pharmacy Curated by ChEMBL | Assay Description Binding affinity for aromatase cytochrome P45019A1 by analysis of Dixon plot | J Med Chem 37: 2198-205 (1994) Article DOI: 10.1021/jm00040a012 BindingDB Entry DOI: 10.7270/Q22F7MG3 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Cytochrome P450 19A1 (503/503 = 100%)† (Homo sapiens (Human)) | BDBM50025428![]() (10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dode...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku College of Pharmacy Curated by ChEMBL | Assay Description In vitro competetitive inhibitory activity was measured on Cytochrome P450 19A1 of human placental microsomes | J Med Chem 37: 2198-205 (1994) Article DOI: 10.1021/jm00040a012 BindingDB Entry DOI: 10.7270/Q22F7MG3 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |