TargetBeta-secretase 1(Homo sapiens (Human))
Research Informatics & Integrative Genomics
Curated by ChEMBL
Research Informatics & Integrative Genomics
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of human BACE1-mediated amyloid beta 42 secretion in human SKNBE2 cells expressing human APP695 after 18 hrs by sandwich alphalisa assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Research Informatics & Integrative Genomics
Curated by ChEMBL
Research Informatics & Integrative Genomics
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of human BACE1-mediated amyloid beta TOT secretion in human SKNBE2 cells expressing human APP695 after 18 hrs by sandwich alphalisa assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Research Informatics & Integrative Genomics
Curated by ChEMBL
Research Informatics & Integrative Genomics
Curated by ChEMBL
Affinity DataIC50: 78nMAssay Description:Inhibition of human BACE1-mediated amyloid beta TOT secretion in human SKNBE2 cells expressing human APP695 after 18 hrs by sandwich alphalisa assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Research Informatics & Integrative Genomics
Curated by ChEMBL
Research Informatics & Integrative Genomics
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:Inhibition of human BACE1-mediated amyloid beta 42 secretion in human SKNBE2 cells expressing human APP695 after 18 hrs by sandwich alphalisa assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Research Informatics & Integrative Genomics
Curated by ChEMBL
Research Informatics & Integrative Genomics
Curated by ChEMBL
Affinity DataIC50: 324nMAssay Description:Inhibition of human recombinant BACE1 using fluorescent Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dnp)-OH peptide as substrate after 1 hr by spectr...More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Research Informatics & Integrative Genomics
Curated by ChEMBL
Research Informatics & Integrative Genomics
Curated by ChEMBL
Affinity DataIC50: 447nMAssay Description:Inhibition of human recombinant BACE1 using fluorescent Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dnp)-OH peptide as substrate after 1 hr by spectr...More data for this Ligand-Target Pair