Affinity Data by PDB ID

PDB code 3V35

Found 1 hit Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Aldose reductase (AR) (316/316 = 100%)^† (Homo sapiens (Human))	BDBM50075050 (Alinia \| NITAZOXANIDE \| Nitazoxanide \| PH-5776) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase DrugBank PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	8.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of human AR				J Med Chem 58: 2047-67 (2015) Article DOI: 10.1021/jm500907a BindingDB Entry DOI: 10.7270/Q2D79D4X
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output