Affinity Data by PDB ID

PDB code 3WZU

Found 1 hit Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dual specificity mitogen-activated protein kinase kinase 7 (MAP2K7) (317/317 = 100%)^† (Homo sapiens (Human))	BDBM50042034 ((5Z)-7-Oxozeaenol \| 5Z-7-Oxozeaenol \| CHEBI:67559 ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Osaka Prefecture University Curated by ChEMBL					Assay Description Inhibition of MAP2K7 (unknown origin) using unphosphorylated GST-tagged JNK1 substrate protein assessed as phosphorylation by ELISA				Bioorg Med Chem Lett 25: 593-6 (2015) Article DOI: 10.1016/j.bmcl.2014.12.011 BindingDB Entry DOI: 10.7270/Q28W3FXP
Osaka Prefecture University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output