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Report error Found 12 Enz. Inhib. hit(s) for PDB: 3KV2
TargetArginase-1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50008099(CHEMBL1234777)
Affinity DataIC50:  450nMAssay Description:Inhibition of recombinant human ARG1 expressed in Escherichia coli using L-arginine hydrochloride as substrate incubated for 1 hr by colorimetric ass...More data for this Ligand-Target Pair
TargetArginase-1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50008099(CHEMBL1234777)
Affinity DataIC50:  517nMAssay Description:Binding affinity to human ARG1 assessed as dissociation constantMore data for this Ligand-Target Pair
TargetArginase-1(Rat)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50008099(CHEMBL1234777)
Affinity DataIC50:  800nMAssay Description:Inhibition of rat Arg1 at pH 7.4More data for this Ligand-Target Pair
TargetArginase-1(Rat)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50008099(CHEMBL1234777)
Affinity DataIC50:  800nMAssay Description:Inhibition of rat ARG1More data for this Ligand-Target Pair
TargetArginase-1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50008099(CHEMBL1234777)
Affinity DataIC50:  1.36E+3nMAssay Description:Inhibition of human recombinant arginase 1 expressed in Escherichia coli BL21 (DE3) assessed as reduction in urea production using L-arginine as subs...More data for this Ligand-Target Pair
TargetArginase-1(Rat)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50008099(CHEMBL1234777)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of rat liver arginaseMore data for this Ligand-Target Pair
TargetArginase-1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50008099(CHEMBL1234777)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human ARG1More data for this Ligand-Target Pair
TargetArginase-1(Bovine)
Univ. Bourgogne Franche-Comt�

Curated by ChEMBL
LigandPNGBDBM50008099(CHEMBL1234777)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of recombinant bovine liver ARGI using L-arginine as substrate incubated for 60 mins by spectroscopic analysisMore data for this Ligand-Target Pair
TargetArginase-1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50008099(CHEMBL1234777)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of recombinant human liver ARGI using L-arginine as substrate incubated for 60 mins by spectroscopic analysisMore data for this Ligand-Target Pair
TargetArginase-1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50008099(CHEMBL1234777)
Affinity DataKd:  50nMAssay Description:Inhibition of human Arginase I assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
TargetArginase-1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50008099(CHEMBL1234777)
Affinity DataKd:  517nMAssay Description:Binding affinity to human Arg1 at pH 8.5More data for this Ligand-Target Pair
TargetArginase-1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50008099(CHEMBL1234777)
Affinity DataKd:  47nMAssay Description:Binding affinity to arginase 1 (unknown origin)More data for this Ligand-Target Pair