Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Bromodomain-containing protein 4 (126/127 > 99%)† (Homo sapiens (Human)) | BDBM50364106![]() (CHEMBL1950957) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of His-6 tagged BRD4 expressed in Escherichia coli after 60 mins by fluorescence anisotropic analysis | J Med Chem 55: 576-86 (2012) Article DOI: 10.1021/jm201320w BindingDB Entry DOI: 10.7270/Q2F47PM1 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |