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Report error Found 5 Enz. Inhib. hit(s) for PDB: 4AWF
TargetPolymerase acidic protein(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50115579((Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid | 2-...)
Affinity DataKi:  480nMAssay Description:Binding affinity to PA N-terminal domain (Competitive)More data for this Ligand-Target Pair
TargetPolymerase acidic protein(Influenza A virus (strain A/X-31 H3N2))
Polo Universitario Ss. Annunziata

Curated by ChEMBL
LigandPNGBDBM50115579((Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid | 2-...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of recombinant Influenza A virus (A/X-31(H3N2)) N-terminal 6xHis-tagged PA-Nter (1 to 217 residues) expressed in Escherichia coli BL21-Cod...More data for this Ligand-Target Pair
TargetPolymerase acidic protein(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50115579((Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid | 2-...)
Affinity DataIC50:  2.13E+4nMAssay Description:Inhibitory concentration against cap-dependent endonuclease activity of influenza virus RNPMore data for this Ligand-Target Pair
TargetPolymerase acidic protein(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50115579((Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid | 2-...)
Affinity DataIC50:  2.13E+4nMAssay Description:Inhibition of cap 1 ALMV primed Influenza transcriptaseMore data for this Ligand-Target Pair
TargetPolymerase acidic protein(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50115579((Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid | 2-...)
Affinity DataEC50:  2.07E+3nMAssay Description:Plaque growth inhibitionMore data for this Ligand-Target Pair