Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) for PDB: 4BKJ
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Affinity DataIC50:  43nMAssay Description:Inhibition of autophosphorylation of DDR1 expressed in HEK293 cells by ELISAMore data for this Ligand-Target Pair
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Affinity DataIC50:  90nMAssay Description:Inhibition of kinobead binding to DDR1 in human K562 cells incubated for 30 mins by iTRAQ reagent-based mass spectrometric methodMore data for this Ligand-Target Pair
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Affinity DataIC50:  337nMAssay Description:Tet inducible human DDR1 over-expressing U2OS was pre-treated by media containing each of the compound for 1 hour and treated by changing the media t...More data for this Ligand-Target Pair
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Affinity DataIC50:  337nMAssay Description:Inhibition of DDR1b (unknown origin) assessed as reduction in collagen-induced DDR1b activationMore data for this Ligand-Target Pair
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of DDR1More data for this Ligand-Target Pair
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Affinity DataKd:  0.700nMAssay Description:Binding constant for DDR1 kinase domainMore data for this Ligand-Target Pair
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Affinity DataKd:  0.700nMAssay Description:Binding constant for DDR1 kinase domainMore data for this Ligand-Target Pair
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Affinity DataKd:  0.700nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair