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Report error Found 2 Enz. Inhib. hit(s) for PDB: 4BU5
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50019165(2-(4'-Hydroxyphenyl)quinazolin-4(3H)-one (2) |...)
Affinity DataIC50:  189nMAssay Description:Inhibition of N-terminal GST-tagged human TNKS-2 (849 to 1166 residues) expressed in in insect sf21 cells preincubated for 2 hrs followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50019165(2-(4'-Hydroxyphenyl)quinazolin-4(3H)-one (2) |...)
Affinity DataIC50:  528nMAssay Description:Inhibition of TNKS-1 (unknown origin) using histone as substrate incubated for 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)