Affinity Data by PDB ID

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PDB code 4BZR

Identical Ligands in BindingDB

Found 4 hits Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Angiotensin-converting enzyme (589/589 = 100%)^† (Homo sapiens (Human))	BDBM50010477 (CHEMBL1233799) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Department of Chemistry Curated by ChEMBL					Assay Description Inhibition of human ACE N-terminal domain using Cbz-Phe-His-Leu-OH substrate				ACS Med Chem Lett 5: 346-51 (2014) Article DOI: 10.1021/ml4004588 BindingDB Entry DOI: 10.7270/Q20C4X8P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Angiotensin-converting enzyme (589/589 = 100%)^† (Homo sapiens (Human))	BDBM50010477 (CHEMBL1233799) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Department of Chemistry Curated by ChEMBL					Assay Description Inhibition of human ACE C-terminal domain using Cbz-Phe-His-Leu-OH substrate				ACS Med Chem Lett 5: 346-51 (2014) Article DOI: 10.1021/ml4004588 BindingDB Entry DOI: 10.7270/Q20C4X8P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Angiotensin-converting enzyme (589/589 = 100%)^† (Homo sapiens (Human))	BDBM50010477 (CHEMBL1233799) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Department of Chemistry Curated by ChEMBL					Assay Description Inhibition of human ACE N-terminal domain using Cbz-Phe-His-Leu-OH substrate				ACS Med Chem Lett 5: 346-51 (2014) Article DOI: 10.1021/ml4004588 BindingDB Entry DOI: 10.7270/Q20C4X8P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Angiotensin-converting enzyme (589/589 = 100%)^† (Homo sapiens (Human))	BDBM50010477 (CHEMBL1233799) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Department of Chemistry Curated by ChEMBL					Assay Description Inhibition of human ACE C-terminal domain using Cbz-Phe-His-Leu-OH substrate				ACS Med Chem Lett 5: 346-51 (2014) Article DOI: 10.1021/ml4004588 BindingDB Entry DOI: 10.7270/Q20C4X8P
					More data for this Ligand-Target Pair				3D Structure (crystal)

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_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output