Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) for PDB: 4DBW
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM50293598(2'-des-methyl indomethacin | CHEMBL503179 | US9346...)
Affinity DataIC50:  0.960nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM50293598(2'-des-methyl indomethacin | CHEMBL503179 | US9346...)
Affinity DataIC50: >100nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM50293598(2'-des-methyl indomethacin | CHEMBL503179 | US9346...)
Affinity DataIC50:  100nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM50293598(2'-des-methyl indomethacin | CHEMBL503179 | US9346...)
Affinity DataIC50:  960nMAssay Description:Inhibition of human recombinant AKR1C3-mediated NADP+-dependent oxidation of S-(+)-1,2,3,4-tetrahydro-1-naphtholMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM50293598(2'-des-methyl indomethacin | CHEMBL503179 | US9346...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant AKR1C1-mediated NADP+-dependent oxidation of S-(+)-1,2,3,4-tetrahydro-1-naphtholMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM50293598(2'-des-methyl indomethacin | CHEMBL503179 | US9346...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of human recombinant AKR1C2-mediated NADP+-dependent oxidation of S-(+)-1,2,3,4-tetrahydro-1-naphtholMore data for this Ligand-Target Pair