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Found 6 Enz. Inhib. hit(s) for PDB: 4DUS
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50383839(CHEMBL2030997)
Affinity DataIC50:  5nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50383839(CHEMBL2030997)
Affinity DataIC50:  5nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50383839(CHEMBL2030997)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant BACE1 using Glu-Ile-Asp-Leu-Met-Val-Leu-Asp as substrate incubated for 60 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50383839(CHEMBL2030997)
Affinity DataIC50:  10nMAssay Description:Inhibition of BACE1 in human HEK293 cells expressing APP Swedish mutant assessed as reduction in amyloid beta 40 production after overnight incubatio...More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50383839(CHEMBL2030997)
Affinity DataIC50:  12nMAssay Description:Inhibition of BACE by cells based assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50383839(CHEMBL2030997)
Affinity DataIC50:  13nMAssay Description:Inhibition of BACE in HEK293 cells by HPLC assayMore data for this Ligand-Target Pair