Found 8 Enz. Inhib. hit(s) for PDB: 4E96 
Affinity DataIC50: 220nMAssay Description:Inhibition of BRD4 isoform 1 by AlphaScreen assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant His-tagged human BRD4 bromodomain 1 expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells preincubated for 30 mins follow...More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Binding affinity to human BRD4 bromodomain 1 using H4Ac4 peptide by amplified luminescent proximity homogeneous assayMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of BRD4 (unknown origin) by Alphascreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 980nMAssay Description:Inhibition of human His-tagged BRD4 BD1 (49 to 170 residues) using H-SGRGK(Ac)GGK(Ac)GLGK-(Ac)GGAK(Ac)RHRK(Biotin)-OH as substrate preincubated for 3...More data for this Ligand-Target Pair
Affinity DataIC50: 3.54E+3nMAssay Description:Inhibition of human BRD4 BD2 (342 to 460 residues) at 30 uM preincubated for 30 mins followed by substrate addition measured after 30 mins by TR-FRET...More data for this Ligand-Target Pair
Affinity DataKd: 136nMAssay Description:Binding affinity to first bromodomain of BRD4 (unknown origin)More data for this Ligand-Target Pair
