Found 6 Enz. Inhib. hit(s) for PDB: 4EGK 
Affinity DataIC50: 19nMAssay Description:Inhibition of HSP90 (unknown origin)More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 150nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
Affinity DataIC50: <200nMAssay Description:Inhibition of ATP-ase activity in human colon tumor cell line (HCT116)More data for this Ligand-Target Pair
Affinity DataKd: 2.20nMAssay Description:Binding affinity to human Hsp90 by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha [1-236](Homo sapiens (Human))
University Of Texas Southwestern Medical Center
University Of Texas Southwestern Medical Center
Affinity DataKd: 46.3nMpH: 7.5 T: 2°CAssay Description:The PDK2 or Hsp90 N-terminal domain protein was dialyzed against 1 liter of thedialysis buffer containing 50 mM Tris-Cl, pH 7.5, 50 mM KCl, 1 mM MgCl...More data for this Ligand-Target Pair
