Found 6 Enz. Inhib. hit(s) for PDB: 4FAL TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of AKR1C3 overexpressed in human HCT116 cells assessed as inhibition of PR-104A conversion to hydroxylamine after 2 hrs by spectrophotomet...More data for this Ligand-Target Pair
3D Structure (crystal)TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1C3 expressed in Escherichia coli BL21(DE3) cells using 8-Acetyl-2,3,5,6-tetrahydro-1H,4H-1...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant His-tagged AKR1C3 expressed in Escherichia coli BL21 (DE3) cells using 8-Acetyl-2,3,5,6-tetrahydro-1H,4H-11-oxa-3a-az...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant His-tagged AKR1C3 expressed in Escherichia coli BL21 (DE3) cells using 8-Acetyl-2,3,5,6-tetrahydro-1H,4H-11-oxa-3a-az...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1C2 expressed in Escherichia coli BL21(DE3) cells using 8-Acetyl-2,3,5,6-tetrahydro-1H,4H-1...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1C1 expressed in Escherichia coli BL21(DE3) cells using 8-Acetyl-2,3,5,6-tetrahydro-1H,4H-1...More data for this Ligand-Target Pair
