Affinity Data by PDB ID

PDB code 4FFW

Found 1 hit Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dipeptidyl peptidase IV (730/730 = 100%)^† (Rattus norvegicus (rat))	BDBM126822 (US8785477, Sitagliptin) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase PC cid PC sid PDB UniChem Similars	PDB US Patent	n/a	n/a	26.0	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Sun-Sail Pharmaceutical Science & Technology Co., Ltd. US Patent					Assay Description Thoroughly mixed test compounds, enzyme and reaction buffer, preincubated the mixture for 15 minutes at 37� C. and then primed reaction by adding sub...				US Patent US8785477 (2014) BindingDB Entry DOI: 10.7270/Q20K278Q
					More data for this Ligand-Target Pair				3D Structure (crystal)

_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output