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Report error Found 2 Enz. Inhib. hit(s) for PDB: 4FNZ
TargetALK tyrosine kinase receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50382660(CHEMBL2023556)
Affinity DataIC50:  16nMAssay Description:Inhibition of human N-terminal GST-fused ALK cytoplasmic domain (1058 to 1620) expressed in SF9 cells using Biotin-Ahx- EQEDEPEGIYGVLF-OH as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetALK tyrosine kinase receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50382660(CHEMBL2023556)
Affinity DataIC50:  59nMAssay Description:Inhibition of ALK phosphorylation in human Karpas-299 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)