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Report error Found 3 Enz. Inhib. hit(s) for PDB: 4FZ6
TargetTyrosine-protein kinase SYK [360-635](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM188161(US9169259, I-43)
Affinity DataIC50:  107nMAssay Description:Assay plates: 96-well MultiScreen 0.65 um filter plates (Millipore Cat. No.: MADVNOB10)Streptavidin coated beads: Streptavidin Sepharose, suspension ...More data for this Ligand-Target Pair
In DepthDetails US Patent
PDB3D3D Structure (crystal)

TargetTyrosine-protein kinase SYK(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50400037(CHEMBL2177733 | US9169259, I-5)
Affinity DataIC50:  127nMAssay Description:Inhibition of human recombinant spleen tyrosine kinase (360 to 635 amino acid residues) after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetTyrosine-protein kinase SYK [360-635](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50400037(CHEMBL2177733 | US9169259, I-5)
Affinity DataIC50:  127nMAssay Description:Assay plates: 96-well MultiScreen 0.65 um filter plates (Millipore Cat. No.: MADVNOB10)Streptavidin coated beads: Streptavidin Sepharose, suspension ...More data for this Ligand-Target Pair
In DepthDetails US Patent
PDB3D3D Structure (crystal)