Found 10 Enz. Inhib. hit(s) for PDB: 4G0U TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro 50% inhibition of topoisomerase II mediated k-DNA decatenationMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 2.76E+3nMAssay Description:Inhibition of human topoisomerase-2B after 2 hrs by ELISAMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Affinity DataEC50: 720nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Affinity DataEC50: 720nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Affinity DataEC50: 720nMAssay Description:In vitro inhibitior of human DNA topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Affinity DataEC50: 720nMAssay Description:Inhibition of topoisomerase II purified from HeLa cellsMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Affinity DataEC50: 720nMAssay Description:Tested for inhibition of topoisomerase II isolated from HeLa cells by DNA-cleavage assayMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Affinity DataEC50: 720nMAssay Description:Inhibitory activity in a cell-free assay of DNA cleavage mediated by purified HeLa cell topoisomerase II.More data for this Ligand-Target Pair
Affinity DataEC50: 1.10E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Affinity DataEC50: 720nMAssay Description:Tested for inhibitory activity against Topoisomerase II isolated from HeLa cells by using SDS-K+ precipitation methodMore data for this Ligand-Target Pair
