Affinity DataKi: 0.0150nM ΔG°: -61.8kJ/molepH: 7.5 T: 25°CAssay Description:The method employed was adapted from the scientific literature and described in detail by Osbourn et al. (1993, Biochemistry, 32, 6229-6236). Recombi...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 0.0150nM ΔG°: -61.8kJ/molepH: 7.5 T: 25°CAssay Description:The method employed was adapted from the scientific literature and described in detail by Osboum et al. (1993, Biochemistry, 32, 6229-6236). Recombin...More data for this Ligand-Target Pair
Affinity DataKi: 0.0150nMpH: 7.5Assay Description:The method employed was adapted from the scientific literature and described in detail by Osbourn et al. (1993, Biochemistry, 32, 6229-6236). Recombi...More data for this Ligand-Target Pair
Affinity DataKi: 0.113nMAssay Description:Apparent inhibition constant for estrogen receptor in Human Breast cancer cytosol in 2.5%DMFMore data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Apparent inhibition constant for estrogen receptor in Human uterine cytosol in 3.3%ethanolMore data for this Ligand-Target Pair
Affinity DataKi: 0.138nMAssay Description:Inhibition of estradiol binding to estrogen receptor in Human Breast cancer cytosol (3.3% ethanol)More data for this Ligand-Target Pair
Affinity DataKi: 0.181nMAssay Description:Apparent inhibition constant for estrogen receptor in Human uterine cytosol in 2.5%DMFMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Displacement of E2-Alexa633 from GFP-tagged ERbeta expressed in COS7 cells by FACSMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]estradiol from full length biotinylated human ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Binding affinity for human estrogen receptor betaMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Ability to displace [3H]-17-beta-estradiol from Estrogen receptor beta by scintillation proximity assay.More data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Relative binding affinity for human estrogen receptor betacompared to [3H]-estradiolMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0100nMAssay Description:In vitro inhibition of estrogen-stimulated MCF-7 cell proliferationMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0460nMAssay Description:Antagonist activity at ERbeta (unknown origin) by cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Displacement of fluorescent labeled 17beta-estradiol from human ERbeta ligand binding domain by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.354nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Displacement of [3H]17-beta-estradiol from Estrogen receptor of rabbit uterine tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 0.579nMAssay Description:Agonist activity at GAL4 DNA-binding domain fused ERbeta (unknown origin) ligand binding domain expressed in UAS-bla GripTite 293 cells assessed as b...More data for this Ligand-Target Pair
Affinity DataIC50: 0.670nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERbeta ligand binding domain expressed in Escherichia coli BL21alpha cells inc...More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibitory activity against Estrogen receptor by displacement of [3H]17-beta-estradiol in ER-rich cytosol from rabbit uterine tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Binding affinity for estrogen receptor of rabbit uterine skeletal muscle tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 0.890nMAssay Description:Antagonist activity at ERbeta (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERbeta by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of fluorescent-labeled E2 from LBD of ERbeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]estradiol from full length human recombinant ERbeta after 3 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of estrogen receptor betaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of binding to recombinant human estrogen receptor betaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Binding affinity towards human recombinant Estrogen receptor beta was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human estrogen receptor 2 using tritiated estradiol incubated for 3 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Binding affinity for human estrogen receptor betaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Binding potency for human ER betaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Binding affinity for human estrogen receptor betaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Binding affinity for human estrogen receptor betaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Binding affinity against human estrogen receptor beta (ER beta) in competitive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Binding affinity to human recombinant ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Binding potency for human ER betaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.18nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbeta expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Binding affinity to human ERbetaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Binding affinity at human recombinant ERbetaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Binding affinity to human ERbetaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Binding affinity to human recombinant ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Binding affinity to ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Binding affinity to ERbetaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of fluoromone binding to recombinant human full length untagged ERbeta expressed in insect cells after 2 hrs by fluorescence polarization ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Binding affinity to human ER betaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMpH: 7.6 T: 22°CAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated polyvinyltoluene scintillation beads (Amersham) and biot...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of [3H]E2 binding to estrogen receptor alpha in MCF-7 cell lysateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Binding affinity for estrogen receptor, by competition with [3H]estradiolMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Displacement of [3H]E2 from GST-fused ERbeta-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to rat ER beta expressed in Escherichia coliMore data for this Ligand-Target Pair
