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Found 3 Enz. Inhib. hit(s) for PDB: 4KAO
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50440358(CHEMBL2425156)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of FAK (unknown origin) using biotinylated-His-TEVhsFAK(31-686)(K454R) as substrate after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50440358(CHEMBL2425156)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAK in human HT-29 cells assessed as Tyr397 phosphorylation after 45 minsMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50440358(CHEMBL2425156)
Affinity DataKd:  770nMAssay Description:Binding affinity to FAK kinase (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair