BindingDB logo
myBDB logout

PDB code 4LV4

Compile Data Set for Download or QSAR

Identical Ligands in BindingDB

Found 2 hits Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fructose-1,6-bisphosphate aldolase (FBA)

  (344/344 = 100%)
(Mycobacterium tuberculosis (strain H37Rv))
BDBM237136
PNG
(US9394254, 5 (HCA))
Show SMILES OC(=O)c1ccc2cccc(O)c2n1
Show InChI InChI=1S/C10H7NO3/c12-8-3-1-2-6-4-5-7(10(13)14)11-9(6)8/h1-5,12H,(H,13,14)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
PDB
UniChem
PDB
US Patent
n/an/a 1.40E+4n/an/an/an/an/an/a



The University of Denver and Regis University

US Patent


Assay Description
Enzymatic activity is measured by contacting the enzyme with a suitable substrate, such as fructose 1,6-bisphosphate, and measuring formation of a pr...


US Patent US9394254 (2016)


BindingDB Entry DOI: 10.7270/Q2251H3W
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Fructose-1,6-bisphosphate aldolase (FBA)

  (344/344 = 100%)
(Mycobacterium tuberculosis (strain H37Rv))
BDBM237136
PNG
(US9394254, 5 (HCA))
Show SMILES OC(=O)c1ccc2cccc(O)c2n1
Show InChI InChI=1S/C10H7NO3/c12-8-3-1-2-6-4-5-7(10(13)14)11-9(6)8/h1-5,12H,(H,13,14)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
PDB
UniChem
PDB
US Patent
n/an/a 1.70E+4 6.94E+3n/an/an/an/an/a



The University of Denver and Regis University

US Patent


Assay Description
Enzymatic activity is measured by contacting the enzyme with a suitable substrate, such as fructose 1,6-bisphosphate, and measuring formation of a pr...


US Patent US9394254 (2016)


BindingDB Entry DOI: 10.7270/Q2251H3W
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)

Identical Ligands in BindingDB

Found 1 hit Isothermal Titration Calorimetry Data
Cell (A)Syringe (B)Cell
Links
Syringe
Links
Cell + Syr
Links
ΔG°
kJ/mole
-TΔS°
kJ/mole
ΔH°
kJ/mole
log KpHTemp
°C
Fructose-1,6-bisphosphate aldolase (FBA)  (344/344 = 100%)

(Mycobacterium tuberculosis (strain H37Rv))
BDBM237136
JPEG
(US9394254, 5 (HCA))
GoogleScholar
PDB
PC cid
PC sid
PDB
n/an/a-28.7n/an/an/a



The University of Denver and Regis University

US Patent




US Patent US9394254 (2016)


Similar Ligands in BindingDB*

Found 1 hit Isothermal Titration Calorimetry Data
Cell (A)Syringe (B)Cell
Links
Syringe
Links
Cell + Syr
Links
ΔG°
kJ/mole
-TΔS°
kJ/mole
ΔH°
kJ/mole
log KpHTemp
°C
Fructose-1,6-bisphosphate aldolase (FBA)  (344/344 = 100%)

(Mycobacterium tuberculosis (strain H37Rv))
BDBM237136
JPEG
(US9394254, 5 (HCA))
GoogleScholar
PDB
PC cid
PC sid
PDB
n/an/a-28.7n/an/an/a



The University of Denver and Regis University

US Patent




US Patent US9394254 (2016)

Search BindingMOAD for More Affinity Data:

* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
Identities from BLAST output