Affinity Data by PDB ID

PDB code 4LYN

Found 1 hit Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
CDK2/CycE (298/298 = 100%)^† (Homo sapiens (Human))	BDBM5685 ((2S)-N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]s...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar	MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute					Assay Description The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...				J Med Chem 45: 3905-27 (2002) Article DOI: 10.1021/jm0201520 BindingDB Entry DOI: 10.7270/Q2GT5KC3
Bristol-Myers Squibb Pharmaceutical Research Institute					More data for this Ligand-Target Pair

_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output