Affinity Data by PDB ID

PDB code 4MR3

Found 1 hit Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Bromodomain-containing protein 4 (126/127 > 99%)^† (Homo sapiens (Human))	BDBM50103503 (CHEMBL2393130) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	645	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of BRD4 bromodomain-1 (unknown origin) by europium based LANCE TR-FRET assay				Bioorg Med Chem 23: 953-9 (2015) Article DOI: 10.1016/j.bmc.2015.01.022 BindingDB Entry DOI: 10.7270/Q26Q201X
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output