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PDB code 4OVF

Compile Data Set for Download or QSAR

Identical Ligands in BindingDB

Found 4 hits Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA polymerase III subunit beta

  (366/366 = 100%)
(Escherichia coli (strain K12))
BDBM50096638
PNG
(CHEMBL3577268)
Show SMILES OC(=O)[C@@H]1CCc2c(C1)[nH]c1ccc(Cl)cc21
Show InChI InChI=1S/C13H12ClNO2/c14-8-2-4-11-10(6-8)9-3-1-7(13(16)17)5-12(9)15-11/h2,4,6-7,15H,1,3,5H2,(H,16,17)/t7-/m1/s1
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UniProtKB/SwissProt

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Article
PubMed
7.40E+4n/an/an/an/an/an/an/an/a



The University of Wollongong and The Illawarra Health and Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli DNA sliding clamp protein using N-fluorescein (FAM)-QLDLF-OH tracer by fluorescence polarization assay


J Med Chem 58: 4693-702 (2015)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
DNA polymerase III subunit beta

  (366/366 = 100%)
(Escherichia coli (strain K12))
BDBM50096641
PNG
(CHEMBL3277053)
Show SMILES OC(=O)C1CCc2c(C1)[nH]c1ccc(Cl)cc21
Show InChI InChI=1S/C13H12ClNO2/c14-8-2-4-11-10(6-8)9-3-1-7(13(16)17)5-12(9)15-11/h2,4,6-7,15H,1,3,5H2,(H,16,17)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
PDB
UniChem

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PDB
Article
PubMed
1.66E+5n/an/an/an/an/an/an/an/a



The University of Wollongong and The Illawarra Health and Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli DNA sliding clamp protein using N-fluorescein (FAM)-QLDLF-OH tracer by fluorescence polarization assay


J Med Chem 58: 4693-702 (2015)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
DNA polymerase III subunit beta

  (366/366 = 100%)
(Escherichia coli (strain K12))
BDBM50096638
PNG
(CHEMBL3577268)
Show SMILES OC(=O)[C@@H]1CCc2c(C1)[nH]c1ccc(Cl)cc21
Show InChI InChI=1S/C13H12ClNO2/c14-8-2-4-11-10(6-8)9-3-1-7(13(16)17)5-12(9)15-11/h2,4,6-7,15H,1,3,5H2,(H,16,17)/t7-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
PDB
UniChem

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PDB
Article
PubMed
n/an/a 1.34E+5n/an/an/an/an/an/a



The University of Wollongong and The Illawarra Health and Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli DNA sliding clamp protein using N-fluorescein (FAM)-QLDLF-OH tracer by fluorescence polarization assay


J Med Chem 58: 4693-702 (2015)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
DNA polymerase III subunit beta

  (366/366 = 100%)
(Escherichia coli (strain K12))
BDBM50096641
PNG
(CHEMBL3277053)
Show SMILES OC(=O)C1CCc2c(C1)[nH]c1ccc(Cl)cc21
Show InChI InChI=1S/C13H12ClNO2/c14-8-2-4-11-10(6-8)9-3-1-7(13(16)17)5-12(9)15-11/h2,4,6-7,15H,1,3,5H2,(H,16,17)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
PDB
UniChem

Patents


Similars

PDB
Article
PubMed
n/an/a 2.99E+5n/an/an/an/an/an/a



The University of Wollongong and The Illawarra Health and Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli DNA sliding clamp protein using N-fluorescein (FAM)-QLDLF-OH tracer by fluorescence polarization assay


J Med Chem 58: 4693-702 (2015)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)

Search BindingMOAD for More Affinity Data:

* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
Identities from BLAST output