Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Enoyl-[acyl-carrier-protein] reductase [NADH] (269/269 = 100%)† (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50373355![]() (CHEMBL264415 | PT10) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | CHEMBL PC cid PC sid PDB UniChem | PDB PubMed | 129 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis InhA | Eur J Med Chem 146: 318-343 (2018) BindingDB Entry DOI: 10.7270/Q2GF0X12 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Enoyl-ACP Reductase (InhA) (269/269 = 100%)† (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50373355![]() (CHEMBL264415 | PT10) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | CHEMBL PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Stony Brook University Curated by ChEMBL | Assay Description Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhA | Bioorg Med Chem Lett 18: 3029-33 (2008) Article DOI: 10.1016/j.bmcl.2008.04.038 BindingDB Entry DOI: 10.7270/Q2SB46KT | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Enoyl-[acyl-carrier-protein] reductase [NADH] (269/269 = 100%)† (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50373355![]() (CHEMBL264415 | PT10) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | CHEMBL PC cid PC sid PDB UniChem | PDB PubMed | n/a | n/a | 182 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Inhibition concentration against human adenosine kinase | Eur J Med Chem 146: 318-343 (2018) BindingDB Entry DOI: 10.7270/Q2GF0X12 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Enoyl-[acyl-carrier-protein] reductase [NADH] (269/269 = 100%)† (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50373355![]() (CHEMBL264415 | PT10) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | CHEMBL PC cid PC sid PDB UniChem | PDB | n/a | n/a | 5.56E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Mycobacterium tuberculosis InhA | Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SC4 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |