Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
GRIA2 (137/143 = 96%)† (Homo sapiens (Human)) | BDBM50060631![]() ((S)-2-Amino-3-(5-nitro-2,4-dioxo-3,4-dihydro-2H-py...) | PDB UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 115 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bristol Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cells | J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Glutamate receptor ionotropic AMPA (101/114 = 89%)† (Homo sapiens (Human)) | BDBM50060631![]() ((S)-2-Amino-3-(5-nitro-2,4-dioxo-3,4-dihydro-2H-py...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 207 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bristol Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 4 expressed in HEK293 cells | J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |