Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Androgen Receptor (258/258 = 100%)† (Homo sapiens (Human)) | BDBM50057651![]() (CHEMBL3326454) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Displacement of [3H]DHT from androgen receptor in human MDA-MB-435 cells after 30 mins | J Med Chem 57: 7396-411 (2014) Article DOI: 10.1021/jm5009049 BindingDB Entry DOI: 10.7270/Q2RB768M | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Androgen Receptor (258/258 = 100%)† (Homo sapiens (Human)) | BDBM50057651![]() (CHEMBL3326454) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Agonist activity at human androgen receptor expressed in mouse C2C12 cells by androgen-specific response element-driven luciferase reporter gene assa... | J Med Chem 57: 7396-411 (2014) Article DOI: 10.1021/jm5009049 BindingDB Entry DOI: 10.7270/Q2RB768M | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |