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Report error Found 3 Enz. Inhib. hit(s) for PDB: 4RSE
TargetRetinoid isomerohydrolase(Bovine)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50546390(CHEMBL4757869 | US20240122876, Example 2)
Affinity DataIC50:  323nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetRetinoid isomerohydrolase/Retinaldehyde-binding protein 1(Human)
Case Western Reserve University

US Patent
LigandPNGBDBM50546390(CHEMBL4757869 | US20240122876, Example 2)
Affinity DataIC50:  323nMAssay Description:Primary amine listed in Table 2 in DMF (1 μL) was added into a suspension containing 300 μg of RPE microsomal proteins, 1% bovine serum alb...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sidPDB
TargetRetinoid isomerohydrolase(Bovine)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50546390(CHEMBL4757869 | US20240122876, Example 2)
Affinity DataEC50:  323nMAssay Description:Inhibition of RPE65 in bovine RPE microsomes assessed as reduction in 11-cis-retinol production using all-trans-retinol as substrate pre-incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB