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Report error Found 2 Enz. Inhib. hit(s) for PDB: 4RSS
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124868(CHEMBL3622958)
Affinity DataIC50:  1.70nMT: 25°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124868(CHEMBL3622958)
Affinity DataIC50:  56nMAssay Description:Inhibition of SYK-mediated TNFalpha production in human IgG-stimulated human THP1 cells incubated for 18 hrs by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)