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Found 3 Enz. Inhib. hit(s) for PDB: 4TZ4
TargetDNA damage-binding protein 1/Protein cereblon(Homo sapiens (Human))
Celgene

LigandPNGBDBM65454(191732-72-6 | CC-5013 | Lenalidomide | Revimid | R...)
Affinity DataIC50:  1.50E+3nMpH: 7.0Assay Description:The 6XHis-tagged full length human CRBN bound to full length human DDB1 used in the assay was purified as described elsewhere with the exception that...More data for this Ligand-Target Pair
TargetProtein cereblon(Homo sapiens (Human))
Celgene

LigandPNGBDBM65454(191732-72-6 | CC-5013 | Lenalidomide | Revimid | R...)
Affinity DataIC50:  2.00E+3nMAssay Description:To measure compound binding to endogenous CRBN.More data for this Ligand-Target Pair
TargetDNA damage-binding protein 1/Protein cereblon(Homo sapiens (Human))
Celgene

LigandPNGBDBM65454(191732-72-6 | CC-5013 | Lenalidomide | Revimid | R...)
Affinity DataIC50:  3.00E+3nMpH: 8.0 T: 2°CAssay Description:Thermal stabilities of CRBN-DDB1 in the presence or absence of phthalimide, thalidomide, lenalidomide and pomalidomide were done in the presence of S...More data for this Ligand-Target Pair