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Found 4 Enz. Inhib. hit(s) for PDB: 4WY1
TargetBeta-secretase 1(Homo sapiens (Human))
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM142369(US8933221, 10)
Affinity DataIC50:  265nMAssay Description:Inhibition of BACE1 in human H4 cells overexpressing APP695 assessed as sAPPbeta level after 18 hrs by ELISAMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM142369(US8933221, 10)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of BACE1 (unknown origin) using biotin-GLTNIKTEEISEISYEVEFR-C[Oregon Green]KK-OH as substrate after 3 hrs by fluorescence polarization ass...More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM142369(US8933221, 10)
Affinity DataIC50:  5.10E+3nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM142391(US8933221, 1)
Affinity DataIC50:  6.70E+3nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair