Affinity Data by PDB ID

PDB code 4XZH

Found 1 hit Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Aldose reductase (269/315 = 85%)^† (Rattus norvegicus)	BDBM50056527 (CHEMBL161556 \| [3-(4-Chloro-3-nitro-benzyl)-2,4-di...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Zoki Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against rat lens aldose reductase(AR).				J Med Chem 40: 684-94 (1997) Article DOI: 10.1021/jm960594+ BindingDB Entry DOI: 10.7270/Q2251H84
Nippon Zoki Pharmaceutical Company Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output