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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Epidermal growth factor receptor (327/327 = 100%)† (Homo sapiens (Human)) | BDBM50029668 (AZD-9291 | OSIMERTINIB | Osimertinib | US10085983,...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Inhibition of EGFR T790M/deletion (746 to 750 residues) mutant (unknown origin) | Bioorg Med Chem Lett 26: 534-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.078 BindingDB Entry DOI: 10.7270/Q2HH6MZQ | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
| Epidermal growth factor receptor (327/327 = 100%)† (Homo sapiens (Human)) | BDBM50029668 (AZD-9291 | OSIMERTINIB | Osimertinib | US10085983,...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Inhibition of EGFR T790M/L858R mutant (unknown origin) | Bioorg Med Chem Lett 26: 534-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.078 BindingDB Entry DOI: 10.7270/Q2HH6MZQ | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Epidermal growth factor receptor (327/327 = 100%)† (Homo sapiens (Human)) | BDBM50029668 (AZD-9291 | OSIMERTINIB | Osimertinib | US10085983,...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Inhibition of wild type EGFR (unknown origin) | Bioorg Med Chem Lett 26: 534-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.078 BindingDB Entry DOI: 10.7270/Q2HH6MZQ | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Epidermal growth factor receptor (327/327 = 100%)† (Homo sapiens (Human)) | BDBM50029668 (AZD-9291 | OSIMERTINIB | Osimertinib | US10085983,...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eberhard Karls University T£bingen Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin incubated ... | J Med Chem 60: 5613-5637 (2017) Article DOI: 10.1021/acs.jmedchem.7b00316 BindingDB Entry DOI: 10.7270/Q2V98BCK | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Epidermal growth factor receptor (327/327 = 100%)† (Homo sapiens (Human)) | BDBM50029668 (AZD-9291 | OSIMERTINIB | Osimertinib | US10085983,...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TU Dortmund University Curated by ChEMBL | Assay Description Reversible inhibition of wild-type human N-terminal GST-tagged EGFR cytoplasmic domain (669 to 1210 end amino acid residues) expressed in baculovirus... | J Med Chem 60: 2361-2372 (2017) Article DOI: 10.1021/acs.jmedchem.6b01626 BindingDB Entry DOI: 10.7270/Q2FB556R | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Epidermal growth factor receptor (327/327 = 100%)† (Homo sapiens (Human)) | BDBM50029668 (AZD-9291 | OSIMERTINIB | Osimertinib | US10085983,...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TU Dortmund University Curated by ChEMBL | Assay Description Inhibition of wild-type human N-terminal GST-tagged EGFR cytoplasmic domain (669 to 1210 end amino acid residues) expressed in baculovirus expression... | J Med Chem 60: 2361-2372 (2017) Article DOI: 10.1021/acs.jmedchem.6b01626 BindingDB Entry DOI: 10.7270/Q2FB556R | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Epidermal growth factor receptor (327/327 = 100%)† (Homo sapiens (Human)) | BDBM50029668 (AZD-9291 | OSIMERTINIB | Osimertinib | US10085983,...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Eberhard Karls University T£bingen Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat... | J Med Chem 60: 5613-5637 (2017) Article DOI: 10.1021/acs.jmedchem.7b00316 BindingDB Entry DOI: 10.7270/Q2V98BCK | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Epidermal growth factor receptor (EGFR)(T790M/L858R) (325/327 > 99%)† (Homo sapiens (Human)) | BDBM50029668 (AZD-9291 | OSIMERTINIB | Osimertinib | US10085983,...) | PDB GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | 25 |
Shanghai Haiyan Pharmaceutical Technology Co., Ltd.; Yangtze River Pharmaceutical Group Co., Ltd. US Patent | Assay Description All reagents used in the following z′-lyte assay were purchased from Invitrogen.The inhibitory activity on T790M/L858R double mutant EGFR kinas... | US Patent US10085983 (2018) Article DOI: 10.1021/jm030233b BindingDB Entry DOI: 10.7270/Q28W3GBG | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Epidermal growth factor receptor (327/327 = 100%)† (Homo sapiens (Human)) | BDBM50029668 (AZD-9291 | OSIMERTINIB | Osimertinib | US10085983,...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | 25 |
Shanghai Haiyan Pharmaceutical Technology Co., Ltd.; Yangtze River Pharmaceutical Group Co., Ltd. US Patent | Assay Description All reagents used in the following z′-lyte assay were purchased from Invitrogen.The inhibitory activity on T790M/L858R double mutant EGFR kinas... | US Patent US10085983 (2018) Article DOI: 10.1021/jm030233b BindingDB Entry DOI: 10.7270/Q28W3GBG | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Epidermal growth factor receptor (327/327 = 100%)† (Homo sapiens (Human)) | BDBM50029668 (AZD-9291 | OSIMERTINIB | Osimertinib | US10085983,...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISA | Bioorg Med Chem 24: 2673-80 (2016) Article DOI: 10.1016/j.bmc.2016.04.032 BindingDB Entry DOI: 10.7270/Q26W9D0T | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Epidermal growth factor receptor (327/327 = 100%)† (Homo sapiens (Human)) | BDBM50029668 (AZD-9291 | OSIMERTINIB | Osimertinib | US10085983,...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of EGFR deletion/T790M mutant autophosphorylation in human PC9-DRH cells after 2 hrs by sandwich ELISA | J Med Chem 59: 2005-24 (2016) Article DOI: 10.1021/acs.jmedchem.5b01633 BindingDB Entry DOI: 10.7270/Q2KS6TDD | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Epidermal growth factor receptor (327/327 = 100%)† (Homo sapiens (Human)) | BDBM50029668 (AZD-9291 | OSIMERTINIB | Osimertinib | US10085983,...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of EGFR T790M/L858R double mutant phosphorylation in human H1975 cells preincubated for 2 hrs by ELISA | Bioorg Med Chem Lett 26: 1861-8 (2016) Article DOI: 10.1016/j.bmcl.2016.02.067 BindingDB Entry DOI: 10.7270/Q2C24Z9V | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Epidermal growth factor receptor (327/327 = 100%)† (Homo sapiens (Human)) | BDBM50029668 (AZD-9291 | OSIMERTINIB | Osimertinib | US10085983,...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of EGFR L858R/T790M double mutant autophosphorylation in human NCI-H1975 cells after 2 hrs by sandwich ELISA | J Med Chem 59: 2005-24 (2016) Article DOI: 10.1021/acs.jmedchem.5b01633 BindingDB Entry DOI: 10.7270/Q2KS6TDD | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Epidermal growth factor receptor (327/327 = 100%)† (Homo sapiens (Human)) | BDBM50029668 (AZD-9291 | OSIMERTINIB | Osimertinib | US10085983,...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of EGFR Del ex19 mutant phosphorylation in human PC9 cells preincubated for 2 hrs by ELISA | Bioorg Med Chem Lett 26: 1861-8 (2016) Article DOI: 10.1016/j.bmcl.2016.02.067 BindingDB Entry DOI: 10.7270/Q2C24Z9V | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Epidermal growth factor receptor (327/327 = 100%)† (Homo sapiens (Human)) | BDBM50029668 (AZD-9291 | OSIMERTINIB | Osimertinib | US10085983,...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of EGFR deletion mutant autophosphorylation in human HCC827 cells after 2 hrs by sandwich ELISA | J Med Chem 59: 2005-24 (2016) Article DOI: 10.1021/acs.jmedchem.5b01633 BindingDB Entry DOI: 10.7270/Q2KS6TDD | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Epidermal growth factor receptor (327/327 = 100%)† (Homo sapiens (Human)) | BDBM50029668 (AZD-9291 | OSIMERTINIB | Osimertinib | US10085983,...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of EGFR L858R mutant autophosphorylation in human H3255 cells after 2 hrs by sandwich ELISA | J Med Chem 59: 2005-24 (2016) Article DOI: 10.1021/acs.jmedchem.5b01633 BindingDB Entry DOI: 10.7270/Q2KS6TDD | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Epidermal growth factor receptor (327/327 = 100%)† (Homo sapiens (Human)) | BDBM50029668 (AZD-9291 | OSIMERTINIB | Osimertinib | US10085983,...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of EGFR deletion mutant autophosphorylation in human PC9 cells after 2 hrs by sandwich ELISA | J Med Chem 59: 2005-24 (2016) Article DOI: 10.1021/acs.jmedchem.5b01633 BindingDB Entry DOI: 10.7270/Q2KS6TDD | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Epidermal growth factor receptor (327/327 = 100%)† (Homo sapiens (Human)) | BDBM50029668 (AZD-9291 | OSIMERTINIB | Osimertinib | US10085983,...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 74 | n/a | n/a | n/a | n/a | n/a | n/a |
Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of wild type EGFR phosphorylation in human HaCaT cells incubated for 3 hrs by ELISA method | J Med Chem 59: 6671-89 (2016) Article DOI: 10.1021/acs.jmedchem.5b01985 BindingDB Entry DOI: 10.7270/Q2RF5X00 | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Epidermal growth factor receptor (327/327 = 100%)† (Homo sapiens (Human)) | BDBM50029668 (AZD-9291 | OSIMERTINIB | Osimertinib | US10085983,...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of EGF-stimulated wild type EGFR autophosphorylation expressed in human A549 cells by sandwich ELISA | J Med Chem 59: 2005-24 (2016) Article DOI: 10.1021/acs.jmedchem.5b01633 BindingDB Entry DOI: 10.7270/Q2KS6TDD | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Epidermal growth factor receptor (327/327 = 100%)† (Homo sapiens (Human)) | BDBM50029668 (AZD-9291 | OSIMERTINIB | Osimertinib | US10085983,...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL | Assay Description Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISA | Eur J Med Chem 126: 1107-1117 (2017) Article DOI: 10.1016/j.ejmech.2016.12.006 BindingDB Entry DOI: 10.7270/Q2F47RD5 | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Epidermal growth factor receptor (327/327 = 100%)† (Homo sapiens (Human)) | BDBM50029668 (AZD-9291 | OSIMERTINIB | Osimertinib | US10085983,...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 409 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISA | Bioorg Med Chem 24: 2673-80 (2016) Article DOI: 10.1016/j.bmc.2016.04.032 BindingDB Entry DOI: 10.7270/Q26W9D0T | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Epidermal growth factor receptor (327/327 = 100%)† (Homo sapiens (Human)) | BDBM50029668 (AZD-9291 | OSIMERTINIB | Osimertinib | US10085983,...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of wild type EGFR phosphorylation in human LoVo cells preincubated for 2 hrs followed by EGF stimulation measured after 30 mins by ELISA | Bioorg Med Chem Lett 26: 1861-8 (2016) Article DOI: 10.1016/j.bmcl.2016.02.067 BindingDB Entry DOI: 10.7270/Q2C24Z9V | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Epidermal growth factor receptor (327/327 = 100%)† (Homo sapiens (Human)) | BDBM50029668 (AZD-9291 | OSIMERTINIB | Osimertinib | US10085983,...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of EGFR L858R/T970M double mutant phosphorylation in human NCI-H1975 cells after 2 hrs by fluorescence assay | J Med Chem 57: 8249-67 (2014) Article DOI: 10.1021/jm500973a BindingDB Entry DOI: 10.7270/Q2ZS2Z4C | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Epidermal growth factor receptor (327/327 = 100%)† (Homo sapiens (Human)) | BDBM50029668 (AZD-9291 | OSIMERTINIB | Osimertinib | US10085983,...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of EGFR exon 19 deletion activating mutant phosphorylation in human PC9 cells after 2 hrs by fluorescence assay | J Med Chem 57: 8249-67 (2014) Article DOI: 10.1021/jm500973a BindingDB Entry DOI: 10.7270/Q2ZS2Z4C | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Epidermal growth factor receptor (327/327 = 100%)† (Homo sapiens (Human)) | BDBM50029668 (AZD-9291 | OSIMERTINIB | Osimertinib | US10085983,...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 4.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of wild type EGFR phosphorylation in human LoVo cells after 2 hrs by fluorescence assay | J Med Chem 57: 8249-67 (2014) Article DOI: 10.1021/jm500973a BindingDB Entry DOI: 10.7270/Q2ZS2Z4C | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Epidermal growth factor receptor (327/327 = 100%)† (Homo sapiens (Human)) | BDBM50029668 (AZD-9291 | OSIMERTINIB | Osimertinib | US10085983,...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 667 | n/a | n/a | n/a | n/a |
TU Dortmund University Curated by ChEMBL | Assay Description Inhibition of wild-type EGFR in human A431 cells assessed as reduction in cell viability after 96 hrs by CellTiterGlo assay | J Med Chem 60: 2361-2372 (2017) Article DOI: 10.1021/acs.jmedchem.6b01626 BindingDB Entry DOI: 10.7270/Q2FB556R | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
