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Report error Found 7 Enz. Inhib. hit(s) for PDB: 4ZGX
TargetCytochrome P450 11B2, mitochondrial(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191903(US9187429, 36 | US9187429, 37 | US9187429, 38)
Affinity DataIC50:  14nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM191903(US9187429, 36 | US9187429, 37 | US9187429, 38)
Affinity DataEC50:  3.14E+4nMAssay Description:G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...More data for this Ligand-Target Pair
In DepthDetails US Patent
PDB3D3D Structure (crystal)

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM191903(US9187429, 36 | US9187429, 37 | US9187429, 38)
Affinity DataEC50:  214nMAssay Description:G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...More data for this Ligand-Target Pair
In DepthDetails US Patent
PDB3D3D Structure (crystal)

TargetCytochrome P450 11B2, mitochondrial(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191903(US9187429, 36 | US9187429, 37 | US9187429, 38)
Affinity DataEC50:  1.26E+3nMAssay Description:G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...More data for this Ligand-Target Pair
In DepthDetails US Patent
PDB3D3D Structure (crystal)

TargetCytochrome P450 11B2, mitochondrial(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191903(US9187429, 36 | US9187429, 37 | US9187429, 38)
Affinity DataEC50:  7nMAssay Description:G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...More data for this Ligand-Target Pair
In DepthDetails US Patent
PDB3D3D Structure (crystal)

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM191903(US9187429, 36 | US9187429, 37 | US9187429, 38)
Affinity DataEC50:  1.01E+3nMAssay Description:G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...More data for this Ligand-Target Pair
In DepthDetails US Patent
PDB3D3D Structure (crystal)

TargetCytochrome P450 11B2, mitochondrial(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191903(US9187429, 36 | US9187429, 37 | US9187429, 38)
Affinity DataEC50:  14nMAssay Description:G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...More data for this Ligand-Target Pair
In DepthDetails US Patent
PDB3D3D Structure (crystal)