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Report error Found 3 Enz. Inhib. hit(s) for PDB: 5DAB
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50117830(CHEMBL3613953)
Affinity DataIC50:  4.95E+3nMT: 25°CAssay Description:Inhibition of FTO (unknown origin) (31 to 505 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in 15-mer ssRNA (5'-CUUG...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50117830(CHEMBL3613953)
Affinity DataIC50:  4.95E+3nMAssay Description:Inhibition of FTO (unknown origin) (31 to 505 residues) mediated demethylation activity expressed in Escherichia coli BL21(DE3) using 15-mer ssRNA ol...More data for this Ligand-Target Pair
In DepthDetails PubMedPDB3D3D Structure (crystal)

TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50117830(CHEMBL3613953)
Affinity DataKd:  1.30E+4nMAssay Description:Binding affinity to FTO (unknown origin) (31 to 505 residues) expressed in Escherichia coli BL21 (DE3) by ITC methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)