Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ionotropic glutamate receptor NMDA 1/2D (RAT) | BDBM18133![]() (2-aminoacetic acid | CHEMBL773 | Glycine | [14C]Gl...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description In vitro inhibitory activity of the compound to inhibit [3H]-glycine binding to NMDA receptor | Bioorg Med Chem Lett 9: 1409-14 (1999) Article DOI: 10.1016/s0960-894x(99)00194-8 BindingDB Entry DOI: 10.7270/Q2W0954Z | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Ionotropic glutamate receptor NMDA 1/2D (RAT) | BDBM18133![]() (2-aminoacetic acid | CHEMBL773 | Glycine | [14C]Gl...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 6.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company Curated by ChEMBL | Assay Description Inhibitory concentration of the compound required to inhibit [3H]-strychnine binding to N-methyl-D-aspartate glutamate receptor 1 | J Med Chem 35: 233-41 (1992) Article DOI: 10.1021/jm00080a006 BindingDB Entry DOI: 10.7270/Q26W9911 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |