Affinity Data by PDB ID

PDB code 5ENK

Found 1 hit Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Beta-secretase 1 (441/441 = 100%)^† (Homo sapiens (Human))	BDBM50088174 (CHEMBL3427251) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Temple University School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of BACE1 in human H4 cells stably transfected with APP751 containing Swedish mutation assessed as reduction in Abeta (1 to 40) and Abeta (...				ACS Med Chem Lett 6: 237-8 (2015)
Temple University School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair

_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output