Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Aurora kinase B (270/276 = 98%)† (Xenopus laevis (African clawed frog)) | BDBM142744![]() (US8937095, 6) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | Purchase PC cid PC sid PDB UniChem Similars | PDB US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | 7.6 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The ATP-KM value of the complex is 61 uM. The kinase assays are run in the presence of 100 uM ATP using 10 uM of a substrate peptide. pAUB-IN847 was ... | US Patent US8937095 (2015) BindingDB Entry DOI: 10.7270/Q2416VS4 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |