Affinity Data by PDB ID

PDB code 5EYK

Found 1 hit Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Aurora kinase B (270/276 = 98%)^† (Xenopus laevis (African clawed frog))	BDBM142744 (US8937095, 6) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase PC cid PC sid PDB UniChem Similars	PDB US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.6	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The ATP-KM value of the complex is 61 uM. The kinase assays are run in the presence of 100 uM ATP using 10 uM of a substrate peptide. pAUB-IN847 was ...				US Patent US8937095 (2015) BindingDB Entry DOI: 10.7270/Q2416VS4
Boehringer Ingelheim International GmbH US Patent					More data for this Ligand-Target Pair				3D Structure (crystal)

_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output